Antioxidative dermocosmetic compositions comprising very low dos

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Cosmetic – antiperspirant – dentifrice

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424 701, 424 705, 514415, A61K 700, A61K 740

Patent

active

059852933

ABSTRACT:
Topically applicable dermocosmetic compositions for improving or maintaining the appearance of human skin or the scalp, comprise a minor antioxidant effective amount of melatonin or analog thereof, formulated into a topically applicable, cosmetically/dermatologically acceptable vehicle, diluent or carrier therefor, such minor antioxidant effective amount being less than 10.sup.-4 % by weight relative to the total weight thereof, e.g., no greater than 0.5.times.10.sup.-4 % or ranging from 10.sup.-12 % to 10.sup.-15 % by weight thereof.

REFERENCES:
patent: 4746674 (1988-05-01), Pierpaoli et al.
patent: 5560917 (1996-10-01), Cohen et al.
Reiter, R. J. Interactions of pieal hormone melatonin with oxygen-centered free radicals: a brief review, Brazilian J. Med. Res. 26:1141-1155, 1993.

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