Antioxidant composition and method for the same

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Conjugate or complex

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A61K 3578

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054984122

ABSTRACT:
A natural antioxidant composition made from a plurality of fermented and milled materials of edible grains and pulses and an embryo or bran of the grains, is produced by a process comprising the steps of: parching a plurality of kinds of edible grains and pulses and an embryo or bran of the grains and pulses respectively; milling the parched resultants separately; steaming the milled resultants separately; molting the steamed resultants separately with fermentations; adding alcohol to the malted resultants separately to restrict the fermentations; drying the resultants separately to remove the alcohol; mixing all of the resultants to make a first mixture fermented; parching an edible seed and a green tea leave separately; milling the parched seed and the parched green tea leave separately; mixing the parched seed and the parched green tea leave to make a second mixture of mash; mixing the first and second mixtures to a mature material; and granulating the mature material to granules, thereby being easily digested in the aged human body without pyrosis or heartburn.

REFERENCES:
patent: 5009891 (1991-04-01), Niwa et al.
patent: 5077069 (1991-12-01), Chang et al.
patent: 5175012 (1992-12-01), Shin et al.
Minamiyama, Y. et al., "Antioxidant Effects of Natural Products (Antioxidant Biofactor; AOB)", The 5th International Congress on Oxygen Radicals: Active Oxygen, Lipid Peroxides and Antioxidants, (Nov. 17-21, 1991).
Komuro, E. et al., "Inhibition of Lipid Peroxidations by Antioxdant Biofactor", Vitamins 67 (9), 455-518 (1993).
Minamiyama, Y. et al., "Antioxidative Effects of a Processed Grain Food; Antioxidant Biofactor (AOB)", 1st World Congress of Dairy Products in Human Health & Nutrition (Jun. 7-10, 1993).
Minamiyama, Y. et al., "Protection by Antioxidant Biofactor (AOB), A Processed Grain Food, of Ischemia-Reperfusion Injury in the Rat Kidney", 1st World Congress of Dairy Products in Human Health and Nutrition (Jun. 7-10, 1993).
Hirai, et al., "Preventive and Antidotal Effects of Antioxidant Biofactor (AOB) on Paraquat-induced Acute Poisoning", 9th Annual Meeting of Japanese Society of Toxicologic Pathology, (1993).
Yoshikawa, T. et al., "Antioxidative Effects of Antioxidant Biofactor; AOB, a Processed Grain Food", Kyoto Prefectural University of Medicine (1992).
Minamiyama, Y. et al., "Free Radical Scavenging Effects of Natural Products (Antioxidant Biofactor; AOB)", 3rd International Symposium on Spin Trapping & Aminoxyl Radical Chemistry, Nov. 22-24, 1991.
Minamiyama, T. et al., "Antioxidant Effects of Natural Products (Antioxidant Biofactor; AOB)", 5th International Congress on Oxygen Radicals (Nov. 17-21, 1991).
Minamiyama, Y., et al., "Superoxide Scavenging Activity and Antioxidative Effect of Antioxidant Biofactor (AOB)", The 15th Japanese Society of Lipid Peroxide and Free Radical Research, (Nov. 1991).
Minamiyama, Y. et al., "A Study of Antioxidant Biofactor (AOB), a Processed Grain Food, on Superoxide Scavenging Activity by ESR Spin Trapping Method", The 8th General Meeting of Medical and Pharmaceutical Society for Wakan-Yaku, (Aug. 1991).
Hirai et al., "Restraint Effect of AOB Against Paraquat Toxicity in Mice (Preliminary Experimentation)", Kanazawa Medical University (1992).
Tanizawa et al., Chem. Pharm. Bull., 32(5), pp. 2011-2014, (1984).
Wang et al., Chung Hsi I Chieh Ito Tsa Chih, 11(3), pp. 159-161 (1991-Mar.).

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