Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1993-09-28
1995-04-11
Henley, III, Raymond
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
A61K 3140
Patent
active
054058635
ABSTRACT:
This invention relates to a new antioxidant use of, and method of treatment using certain hydroxycarbazole compounds or a pharmaceutically acceptable salt thereof. More specifically, the compounds are useful for the prevention of oxidative tissue damage to organs, particularly the central nervous system including the brain, in mammals afflicted with disease-induced ischemic trauma, particularly stroke.
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Lysko et al., Chemical Abstracts 118(7):52140v, Jun. 1992.
Hoeher et al., Chemcial Abstracts 111(23):208919z, Apr. 1989.
Hamburger et al., Chemical Abstracts 115(19):198096v, Mar. 1991.
Hashimoto et al., Chemical Abstracts 116(1) 469y, Mar. 1991.
Barone Frank C.
Feuerstein Giora
Yue Tian-Li
Henley III Raymond
Jarvis William R. A.
Lentz Edward T.
SmithKline Beecham Corporation
Stercho Yuriy P.
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