Antioxidant, antiphospholipase derivatives of ricinoleic acid

Details Antioxidant, antiphospholipase derivatives of ricinoleic acid Antioxidant, antiphospholipase derivatives of ricinoleic acid

1995-06-06

1997-08-19

Carr, Deborah D.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

548537, 549 70, 549 77, 549 72, 549 80, 549487, 554 56, 554 57, 554 58, 554110, 554111, 554219, 554229, C07D20700, C07D29500

Patent

active

056590490

ABSTRACT:
Water or lipid soluble, pharmacologically active, antioxidant, anti-phospholipase compounds that are chemically defined. The compounds protect mammalian cells by inhibiting PLA.sub.2 and preventing oxidation. In particular, each compound has at least two fatty moieties and no active hydroxy group. The compound may also have at least one ionizable group, which may a carboxyl group, and each of the fatty moieties has from sixteen to twenty carbon atoms and at least one cis-unsaturated double bond.

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