Drug – bio-affecting and body treating compositions – Topical sun or radiation screening – or tanning preparations
Patent
1998-12-24
2000-11-14
Dodson, Shelley A.
Drug, bio-affecting and body treating compositions
Topical sun or radiation screening, or tanning preparations
424400, 424401, A61K 742, A61K 700
Patent
active
061466166
DESCRIPTION:
BRIEF SUMMARY
The subject of the present invention is new compositions based on lupine oil, or on fractions thereof, especially concentrates and unsaponifiable matter.
Lupine oil may be extracted especially from lupine meals and/or seeds.
Lupine is a close relative of the pea, broad bean, soybean and French bean. The seed is traditionally used as human food for its high protein content. It is also incorporated into ruminant feed in the form of a whole plant or of its seeds and is also frequently used as green manure. More particularly, four species of lupine are of real agronomic importance: white lupine (lupinus albus), blue lupine (lupinus angusti-folius), yellow lupine (lupinus luteus) and South American lupine (lupinus mutabilis).
Plants constitute an abundant lipid source and the extraction of vegetable oil has already been widely carried out. The oil can then be used directly, or in the form of some of its fractions. Among the fractions which can be obtained from a vegetable oil, there may be mentioned the unsaponifiable matter or the concentrates.
According to the European Pharmacopeia, 2nd edition, page V.3.4.7, the term "unsaponifiable" applies to the nonvolatile substances obtained by extraction, with an organic solvent, of a solution of the substance to be examined after saponification of a vegetable or animal oil.
Moreover, the so-called molecular distillation method makes it possible to concentrate oils derived in particular from plants (vegetable oils), and to obtain concentrates in which the concentration of unsaponifiable matter may reach, for example, the order of 10% to 20% by weight, or even greater, this concentration being of the order of 1% to 2% by weight in the original oils.
Vegetable oils have thus been the subject of various uses, mainly in cosmetology. For example, Patent FR 92 07830 describes the preparation of compositions based on unsaponifiable fractions of wheatgerm and sesame oils for a cosmetic use, these concentrates being obtained by molecular distillation according to a preferred method described in the patent.
As regards lupine oil, no cosmetic or pharmaceutical use has been envisaged up to date. European Patent Publication EP-A-441672 describes a process for the extraction of constituents of a plant material which make it possible in particular to obtain a lupine oil without any trace of alkaloid. This document describes in particular the treatment of the bitter lupine seeds and aims essentially to enhance the value of a protein cake free of the bitterness characteristic of bitter lupine seeds.
The inventors have now observed that, surprisingly, a composition containing lupine oil or one or more fractions thereof had a number of properties paving the way to a variety of applications in the cosmetic, pharmaceutical or food domain.
The studies on which the invention is based have made it possible to demonstrate that lupine oil or its fractions exert especially an antioxidant and antielastase activity.
The subject of the present invention is therefore an antioxidant and/or antielastase composition containing lupine oil or one or more fractions thereof. The lupine oil may be extracted from lupine meals and/or seeds.
The lupine oil may be obtained by any known method, in particular by direct pressing of the lupine seeds.
So-called sweet lupine species, that is to say free of bitterness, will be preferably used as raw material for the production of the lupine oil or of its fractions. There may be mentioned especially white lupine, blue lupine, yellow lupine and South American lupine, in particular white lupine (lupinus albus). The lupine oil extracted from this lupine variety is then free of undesirable alkaloids.
The invention relates more particularly to a composition comprising lupine oil in the form of a fraction consisting of a lupine oil concentrate obtained by molecular distillation of said oil.
According to a preferred embodiment, the compositions based on lupine oil according to the invention comprise one or more lupine oil fractions in the form of unsaponifiable matter as cont
REFERENCES:
"Use of Lupine as a Protein-Oil Food Source," Fichier Chemical Abstracts, vol. 102, AN 77429, XP-002052109 (1983).
"Lupine Oil--Its Use as Food," Fichier Chemical Abstracts, vol. 101, AN 150094, XP-002052110, (1984).
Montaudoin Marie-Georgette
Msika Philippe
Rancurel Alain
Dodson Shelley A.
Laboratories Pharmascience
LandOfFree
Antioxidant and/or antielastase composition based on lupine oil does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Antioxidant and/or antielastase composition based on lupine oil, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Antioxidant and/or antielastase composition based on lupine oil will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2062244