Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1993-04-16
1995-05-09
Cintins, Marianne M.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514292, 546 64, 546 84, A61K 3144, C07D47100
Patent
active
054140013
ABSTRACT:
The invention discloses certain antitumor pyrrolo[4,3,2-de]quinolin-8(1H)-ones isolated from the Fijian marine sponge Z. cf. marsailis and structurally modified compounds thereof and pharmaceutical compositions.
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Stierle, D. B.; Faulkner, D. J. "J. Nat. Prod.", 1991, 54, 1131.
Kobayashi, J.; Cheng, J.; Ishibashi, M.; Nakamura, H.; Ohizumi, Y.; Hirata, Y.; Sasaki, T.; Lu, H.; Clardy, J. "Tetrahedron Lett." 1987, 28, 4939.
Cheng, J.; Ohizumi, Y.; Walchli, M. R.; Nakamura, H.; Hirata, Y.; Sasaki, T.; Kobayashi, J. "J. Org. Chem." 1988, 53, 4621.
Kobayashi, J.; Cheng, J.; Yamamura, S.; Ishibashi, M. "Tetrahedron Lett." 1991, 32, 1227.
Kobayashi et al, Tetrahedron Letters, 32(9) pp. 1227-1228, 1991.
Barrows Louis R.
Ireland Chris M.
Kramer Robert
Radisky Derek C.
American Cyanamid Company
Cintins Marianne M.
Spivack Phyllis G.
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