Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1980-08-25
1982-03-30
Daus, Donald G.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
2602444, A61K 31475, C07D51904
Patent
active
043223516
ABSTRACT:
4'-Substituted VLB and vincristine, 4-desacetyl VLB, 4-desacetylvincristine and amides and hydrazides thereof, prepared by action of HCN or acetonitrile under strongly acidic conditions.
REFERENCES:
patent: 4075214 (1978-02-01), Katner et al.
patent: 4166810 (1979-09-01), Cullinan et al.
patent: 4203898 (1980-05-01), Cullinan et al.
Mangeney et al., J. Am. Chem. Soc., vol. 101, No. 8, pp. 2243-2245, 4/11/79.
Conrad, et al., J. Med. Chem., vol. 22, No. 4, pp. 391-400, (1979).
Gerzon Koert
Miller Jean C.
Daus Donald G.
Eli Lilly and Company
Rivers Diana G.
Rowe James Lincoln
Whale Arthur R.
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