Antimutagenic compositions for treatment and prevention of...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

Reissue Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C514S046000, C514S047000, C514S048000, C514S049000, C514S050000, C514S051000, C514S944000, C514S969000

Reissue Patent

active

10887555

ABSTRACT:
A method of improving DNA repair and reducing DNA damage and for reducing mutation frequency in skin for the purpose of reducing consequences of exposure to solar or ultraviolet radiation is disclosed. The methods comprise administering to the skin a composition containing deoxyribonucleosides in concentrations sufficient to enhance DNA repair or reduce mutation frequency in a vehicle capable of delivering effective amounts of deoxyribonucleosides to the necessary skin cells.

REFERENCES:
patent: 3937809 (1976-02-01), Jacobi
patent: 4537776 (1985-08-01), Cooper
patent: 4557934 (1985-12-01), Cooper
patent: 5246708 (1993-09-01), von Borstel et al.
patent: 5250290 (1993-10-01), Giacomoni et al.
patent: 5691320 (1997-11-01), von Borstel et al.
patent: 5770582 (1998-06-01), von Borstel
patent: 6020320 (2000-02-01), von Borstel et al.
patent: 6020322 (2000-02-01), von Borstel et al.
patent: 6060459 (2000-05-01), von Borstel et al.
patent: 6277892 (2001-08-01), Deckner et al.
patent: 89/03838 (1989-05-01), None
patent: 94/13687 (1994-06-01), None
patent: 94/26761 (1994-11-01), None
patent: 95/01773 (1995-01-01), None
patent: 96/01115 (1996-01-01), None
patent: 00/11952 (2000-03-01), None
Collins, Andrew R.S., et al,J. Cell. Physiol., 99: 125-138 (1979) “Repair and Survival after UV in Quiescent and Proliferating Microtus agrestis Cells: Different Rates of Incision and Different Dependence on DNA Precursor Supply”.
Pashko, Laura L., et al,Carcinogenesis, vol. 12, No. 11, pp. 2189-2192, 1991 “Inhibition of 12-O-tetradecanoylphorbol-13-acetate-oromoted skin tumor formation in mice by 15∀-fluoro-5-androsten-17-one and its reversal by deoxyribonucleosides”.
Yew, Foch F.-H., et al,Biochimica et Biophysica Acta, 562 (1979) 240-251 “Ultraviolet-Induced DNA Excision Repair in Human Bandt Lymphocytes”.
Musk, P., et al,Mutation Research, 227 (1989) 25-30, “Solar and UVC-induced mutation in human cells and inhibition by deoxynucleosides”.
Bianchi, Vera, et al,Mutation Research, 146 (1985) 227-284, “Accuracy of UV-induced DNA repair in V79 cells with imbalance of deoxynucleotide pools”.
Leder, Aya, et al,Proc. Natl. Sci. USA, vol. 87. pp. 9178-9182, Dec. 1990 Genetics, “v-Ha-ras transgene abrogates the initiation step in mouse skin tumorigenesis: Effects of phorbol esters and retionic acid”.
Nature, vol. 372, Dec. 1, 1994, pp. 413-414, “DNA damage and melanogenesis”.
Green, Michael H.L., et al,Mutation Research, DNA Repair, 315 (1994) 25-32, “Effect of deoxyribonucleosides on the hypersensitivity of human peripheral blood lymphocytes to UV-B and UV-C irradiation”.
Kwon, Nyoun Soo, et al,J. Exp. Med., The Rockefeller University Press, vol. 174, Oct. 1991, pp. 761-767, “Inhibition of tumor Cell Ribonucleotide by Macrophage-derived Nitric Oxide”.
Newman, C.N., et al,Mutation Research, 200 (1988) 201-206, “Modulation of DNA precursor pools, DNA synthesis, and ultraviolet sensitivity of a repair-deficient CHO cell line by deoxycytidine”.
Oliver, F. Javier, et al,Biochem. J., (1996) 316, 421-425, “Regulation of the salvage pathway of deoxynucleotides synthesis in apoptosis induced by growth factor deprivation”.
McKelvey, Valerie June, et al,Leukemia Research, vol. 12, No. 2, pp. 167-171, 1988, “Synergism Between U.V. and Thymidine Treatments in the Induction of Cytogenetic Damage in Wild-Type Friend Erythroleukaemia Cells”.
Yarosh, Daniel, et al,Applied Genetics, Inc., (1992) pp. 4227-4231, “Pyrimidine Dimer Removal Enhanced by DNA Repair Liposomes Reduces the Incidence of UV Skin Cancer in Mice”.
Bianchi, Vera, et al,Mutation Research, 146 (1985) 277-284, “Accuracy of UV-induced DNA repair in V79 cells with imbalance of deoxynucleotide pools”.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Antimutagenic compositions for treatment and prevention of... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Antimutagenic compositions for treatment and prevention of..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Antimutagenic compositions for treatment and prevention of... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3726751

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.