Antimigraine derivatives of indolylcycloalkanylamines

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514256, 514269, 514415, 544242, 544298, 544319, 544330, 544333, 546273, 5462774, 548469, 548509, 548510, 548511, A61K 3144, C07D40110

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active

055831494

ABSTRACT:
A series of novel serotonergic indolyl derivatives of cycloalkanyl- and cycloalkenyl-amines of Formula I are intended for use in the alleviation of vascular headaches. ##STR1##

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patent: 4954502 (1990-09-01), Smith et al.
patent: 5124332 (1992-06-01), Wise et al.
Chemical Abstracts, vol. 65, No. 5, Aug. 29, 1966.
Glennon et al, "5-HT1D Serotonin Receptors: Results of a Structure-Affinity Investigation," Drug Development Research, vol. 22, 1991, pp. 25-36.

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