Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1993-09-16
1995-01-17
Lee, Mary C.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
548504, A61K 3140, C07D20916
Patent
active
053825926
ABSTRACT:
A series of serotonergic 5-cyclobutenedionylamino-substituted tryptamine derivatives of Formula I is disclosed for use in the alleviation of vascular headaches. ##STR1## The formula I substituents, as further defined in the specification, are: R.sup.1 is hydrogen, halogen, and alkyl; R.sup.2 and R.sup.3 can be hydrogen or alkyl; R.sup.4 is hydrogen, alkyl, acyl or alkylsulfonyl; m is 0 to 3 and n is 1 to 5; and X is amino, alkoxy, hydrogen, alkyl, aryl or alkylaryl.
Gylys Jonas A.
Ruediger Edward H.
Smith David W.
Solomon Carola
Yevich Joseph P.
Bristol--Myers Squibb Company
Haley Jacqueline
Lee Mary C.
Ryan Richard P.
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