Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1994-04-26
1995-07-18
Shah, Mukund J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514253, 514300, 514414, 548453, 549364, 546122, 544349, A61K 31495, A61K 31505, C07D40306, C07D40314
Patent
active
054341540
ABSTRACT:
A series of novel alkoxypyridin-4-yl and alkoxypyrimidin-4-yl derivatives of indol-3-ylalkylpiperazines of Formula I are intended to be useful agents ##STR1## for alleviation of vascular headache on the basis of their potent affinity and agonist activity at 5-HT1D binding sites.
REFERENCES:
patent: 3188313 (1965-06-01), Archer
patent: 3562278 (1971-02-01), Archer
patent: 5010079 (1991-04-01), Manoury et al.
patent: 5077293 (1991-12-01), Smith et al.
AMA Drug Evalutaions 6th Edition, 1986, pp. 239-253 W. B. Saunders Co., Philadelphia, Pa.
Journal of Medicinal Chemistry, vol. 30, No. 1, 1987, pp. 1-12; Central Serotonin Receptors as Targets for Drug Research.
"Drugs Used to Treat Migraine and Other Headaches," AMA Drug Evaluations, 6th edition, 1986, pp. 239-253, W. B. Saunders Co., Philadelphia, Pa.
"Central Serotion Receptors as Targets for Drug Research," Journal of Medicinal Chemistry, vol. 30, No. 1, 1987, pp. 1-12.
Combrink Keith D.
Pearce Bradley C.
Ruediger Edward H.
Smith David W.
Williams Andrew
Bristol--Myers Squibb Company
Grumbling Matthew V.
Ryan Richard P.
Shah Mukund J.
LandOfFree
Antimigraine 4-pyrimidinyl and pyridinyl derivatives of indol-3y does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Antimigraine 4-pyrimidinyl and pyridinyl derivatives of indol-3y, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Antimigraine 4-pyrimidinyl and pyridinyl derivatives of indol-3y will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2419082