Antimicrobials against pathogenic bacteria and method for...

Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 6 to 7 amino acid residues in defined sequence

Reexamination Certificate

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C514S002600

Reexamination Certificate

active

07544773

ABSTRACT:
The present invention provides antimicrobials for efficient therapy of infections caused by bacterial pathogens. The antimicrobials include peptides corresponding to the active site of N-terminal extension of subunits composing specific adhesive organelles of virulence of pathogenic bacteria. These antimicrobial peptides inhibit surface expression of adhesive organelles and thus prevent development of infections caused by pathogenic bacteria. The invention describes also effective methods for screening molecules inhibiting the generation of the adhesive organelles.

REFERENCES:
patent: 5843450 (1998-12-01), Dawson et al.
patent: 6001823 (1999-12-01), Hultgren et al.
patent: WO95/14028 (1995-05-01), None
patent: WO 0032785 (2000-06-01), None
patent: WO01/10386 (2001-02-01), None
patent: WO 02077183 (2002-10-01), None
Hochheimer A. et al. “The Tungsten FormylMethanofuran Dehydrogenase From Methanobacterium thermoautotrophicum Contains Sequence Motifs Characteristic for Enzymes Containing Molybdenum Dinucleotide” 1995, Eur. J. Biochem. vol. 234, pp. 910-920.
Zavyalov V.P et al. Specific high affinity binding of human interleukin . . . FEBS Letters 371 (1995) 65-68.
Flemmer K et al. Peptides inhibit complexation of the bacterial . . . Bioorganic & Medicinal Chemistry Letters 1995, vol. 5:9 927-932.
Zavialov A V. 2001 Secretion of recombinant proteins via . . . Applied and Environmental Microbiology 2001, p. 1805-1814.
Zavialov AV et al. 2003 Structure and Biogenesis of the Capsular F1 . . . Cell 113: 587-596.
Zavialov AV et al 2002 Donor strand complementation mechanim . . . Molecular Microbiology 45(1) 983-.
Zavialov et al. (2001) Secretion of recombinant proteins via Chperone/usher . . . Appl: and Env. Microbiology 67(4) 1805-1814.
Zavyalov et al. (1995) Specific high affinity binding of human interleukin . . . FEBS LEtt. 371: 65-68.
Zavyalov et al. (2003) Stucture and Biogenesis of the Capsular F1 Antigen fromYersinia pestis. . . Cell 113, pp. 587-596.
Flemmer K et al.(1995) Peptides inhibit complexation of the bacterial . . . Biorganic & MEdical Chemistry Letters.vol. 5 (9) pp. 927-932.

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