Antimicrobial Toothpaste

Drug – bio-affecting and body treating compositions – Dentifrices – Fluorine or fluorine compound containing

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424 49, 424 58, A61K 716, A61K 718, A61K 726

Patent

active

050948431

ABSTRACT:
A storage stable, anti-plaque and anti-gingivitis toothpaste comprises an amount.

REFERENCES:
patent: 1526940 (1925-02-01), Staegemann
patent: 3164524 (1965-01-01), Fand et al.
patent: 4209505 (1980-06-01), Mikhail
patent: 4272513 (1981-06-01), Gaffar
patent: 4645662 (1987-02-01), Nakashima et al.
patent: 4716036 (1987-12-01), Schelm
patent: 4830221 (1989-05-01), Mazzanobile
patent: 4945087 (1990-07-01), Talwar et al.
patent: 4950479 (1990-08-01), Hill et al.
patent: 4973472 (1990-11-01), Morisaki
"Euthymol Toothpaste", sold only in the U.K. (unpublished analysis shows: 0.12% Thymol, 1.26% Methyl Salicylate, 0.07% Menthol, and 0.012% Eucalyptol).
Axelson et al, J. Clin. Periodontol, 14(4):205-212 (1987), in B.A., 84: 18507 (1987).
DePaola et al., J. Clin. Periodontol 16(5): 311-315 (1989) in B.A. 88:23479 (1989).
Overholser et al., J. Clin. Periodontol. 17(8):575-579 (1990) in GA. 114:493352 (1991).
"Approval of Listerine, the Background", Biological Therapies in Dentistry, vol. 3, No. 11, Apr. 1988 (approved in 1987) pp. 37-40.
Reg.T.M. 58085 Dec. 4, 1906 (Parke Davis & Co) "Euthymol Dentifrice Paste", First Used in Commerce Jan. 1896 (in third renewal).

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