Antimicrobial sterol conjugates

Details Antimicrobial sterol conjugates Antimicrobial sterol conjugates

1995-05-30

1996-12-10

Prior, Kimberly J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Cyclopentanohydrophenanthrene ring system containing

552636, C07J 900, C07J 100

Patent

active

055832393

ABSTRACT:
The invention discloses steroid conjugates having the following structure: ##STR1## where Y is NHCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 NH.sub.2, NH(CH.sub.2).sub.3 NH(CH.sub.2).sub.4 NH(CH.sub.2).sub.3 NH.sub.2, or NHCH.sub.2 CH.sub.2 NHCH.sub.2 CH.sub.2 NHCH.sub.2 CH.sub.2 NH.sub.2, and each of R.sub.1, R.sub.2, R.sub.3 and R.sub.4 is individually H, OH and OSO.sub.3 H. These conjugates posses antimicrobial properties and are, therefore, useful as antibiotics.

REFERENCES:
patent: 5122520 (1992-06-01), Azria et al.
patent: 5352682 (1994-10-01), Sipos

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