Antimicrobial salt of fosfomycin with imidazole

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Phosphorus containing other than solely as part of an...

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514 99, 548335, 548341, 548342, 548346, A61K 31685, C07D23358

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active

046753150

ABSTRACT:
Novel salts of the formula ##STR1## are disclosed wherein n is 1 or 2; both OR groups are O.sup.- when n is 2, or one is O.sup.- and one is OH when n is 1; and R.sub.1, R.sub.2, R.sub.3, and R.sub.4 independently represent hydrogen, alkyl, aryl, amino-alkyl, hydroxy-alkyl, or hydroxy-alkyl-amino. These salts are useful in treatment of microbial infecting in mammals, and use of the salts in composition for oral and parenteral administration is also disclosed.

REFERENCES:
patent: 2750379 (1956-06-01), Hanslick et al.
patent: 2801243 (1957-07-01), Hanslick et al.
Chemical Abstracts, 91:158099c (1979) [Ger. 2,820,794, 5/23/79].

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