Antimicrobial polymeric surfaces

Details Antimicrobial polymeric surfaces Antimicrobial polymeric surfaces

2006-12-19

2006-12-19

Mulcahy, Peter D. (Department: 1713)

Synthetic resins or natural rubbers -- part of the class 520 ser

Synthetic resins

Mixing of two or more solid polymers; mixing of solid...

C427S002110, C427S002120, C427S002240, C427S002250, C427S002280, C428S448000, C525S182000, C525S186000, C525S203000, C525S421000, C525S445000

Reexamination Certificate

active

07151139

ABSTRACT:
Bactericidal compositions are disclosed that comprise a polymeric compound immobilized on a material. Medical devices are also disclosed which comprise such a bactericidal composition. Methods are disclosed for covalently derivatizing the surfaces of common materials with an antibacterial polycation, e.g., poly(vinyl-N-pyridinium bromide); the first step of the methods involves coating the surface with a nanolayer of silica. Various commercial synthetic polymers derivatized in this manner are bactericidal, i.e., they kill on contact up to 99% of deposited Gram-positive and Gram-negative bacteria, whether deposited through air or water.

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