Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1996-07-26
1999-01-05
Marschel, Ardin H.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
435 693, 530300, 530350, 536 231, 800205, 800250, 935 88, C12P 2100
Patent
active
058561277
ABSTRACT:
The present invention is directed to antimicrobial polypeptides and to nucleic acid molecules encoding these antimicrobial polypeptides. The polypeptide consists of from 15 to 20 amino acids and has an amphipathic alpha helix structure, wherein 3 or more of the amino acids form a positively charged domain extending axially along the alpha helix. Expression vectors, host cells, and transgenic plants, as well as methods of producing plants having improved resistance to fungal and bacterial infestation, are also provided.
REFERENCES:
patent: 5428147 (1995-06-01), Logemann et al.
patent: 5451514 (1995-09-01), Boudet et al.
patent: 5516671 (1996-05-01), Lawrence et al.
patent: 5607914 (1997-03-01), Rao et al.
Agerberth, B., et al., Eur J Biochem 202: 849-854 (1991).
ASM News, vol. 60, No. 8, pp. 412-413 (1994).
Bessalle, R., et al., J Med Chem 36: 1203-1209 (1993).
Bevins, C.L., et al., Annu Rev. Biochem 59: 395-414 (1990).
Blondelle, S.E., et al., Biochemistry 30: 4671-4678 (1991).
Boman, H.G., et al., FEBS Letters 259(1): 103-106 (1989).
Broekaert, W.F., et al., Biochemistry 31: 4308-4314 (1992).
Campbell, W.H., et al., Plant Physiol 92: 1-11 (1990).
Chen, H.-C., et al., FEBS Letters 236(2): 462-466 (1988).
Christensen, B., et al., Proc Natl Acad Sci USA 85: 5072-5076 (1988).
Cornelissen, B.J.C., et al., Plant Physiol 101: 709-712 (1993).
Soravia, E., et al., FEBS Letters 228(2): 337-340 (1988).
Zasloff, M., Proc Natl Acad Sci USA 84:5449-5453 (1987).
Powell et al. (1995) Molecular Plant-Microbe Interactions, vol. 8, No. 5, pp. 792-794. (1970)!, p. 71.
Maynard Charles A.
Powell William Allen
Braman, Esq. Susan J.
Marschel Ardin H.
The Research Foundation of State University of New York
LandOfFree
Antimicrobial peptides does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Antimicrobial peptides, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Antimicrobial peptides will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-861195