Antimicrobial liquid preservative solutions and process for prep

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514390, 514478, 514479, A01N 4350, A01N 4710

Patent

active

059655941

ABSTRACT:
Improved liquid antimicrobial solutions useful as preservative additives to personal care preparations, particularly cosmetic formulations and the like, are provided which comprise 1,3-dimethylol-5,5-disubstituted hydantoin, liquid aromatic alcohol, and iodoalkynyl alkyl carbamate. A preferred antimicrobial solution can be prepared by producing the 1,3,dimethylol-5,5-disubstituted hydantoin in situ in the selected liquid aromatic alcohol and then adding to the resulting solution the previously prepared iodoalkynyl alkyl carbamate. The solutions are surprisingly water dispersible and display broad spectrum antimicrobial effectiveness, particularly antifungal effectiveness, at a relatively low usage concentration in a cosmetic medium.

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