Antimicrobial/endotoxin neutralizing polypeptide

Details Antimicrobial/endotoxin neutralizing polypeptide Antimicrobial/endotoxin neutralizing polypeptide

2007-07-17

2007-07-17

Navarro, Mark (Department: 1645)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

C514S008100, C530S300000

Reexamination Certificate

active

10145651

ABSTRACT:
The present invention provides a therapeutic method for treating or preventing a disease resulting from a microbial infection in an individual using an antimicrobial polypeptide. The present invention also provides a method of potentiating the therapeutic action of an antimicrobial drug in a patient. Further provided in the present invention are methods for neutralizing circulating endotoxin in a patient by administering the endotoxin-neutralizing polypeptide or functional variant thereof of the present invention to the patient.

REFERENCES:
patent: 4977137 (1990-12-01), Nichols et al.
patent: 5198419 (1993-03-01), Ando et al.
patent: 5214028 (1993-05-01), Tomita et al.
patent: 5240909 (1993-08-01), Nitsche
patent: 5304633 (1994-04-01), Tomita et al.
patent: 5317084 (1994-05-01), Tomita et al.
patent: 5330975 (1994-07-01), Isoda et al.
patent: 5531989 (1996-07-01), Paul
patent: 5561109 (1996-10-01), Mita et al.
patent: 5571691 (1996-11-01), Conneely et al.
patent: 5571697 (1996-11-01), Conneely et al.
patent: 5571896 (1996-11-01), Conneely et al.
patent: 5576299 (1996-11-01), Ando et al.
patent: 5656591 (1997-08-01), Tomita et al.
patent: 5712247 (1998-01-01), Wu et al.
patent: 5725864 (1998-03-01), Yamamoto et al.
patent: 5766939 (1998-06-01), Conneely et al.
patent: 5834424 (1998-11-01), Valenti et al.
patent: 5849881 (1998-12-01), Conneely et al.
patent: 5849885 (1998-12-01), Nuyens et al.
patent: 5919913 (1999-07-01), Nuyens et al.
patent: 5955316 (1999-09-01), Conneely et al.
patent: 6080559 (2000-06-01), Conneely et al.
patent: 6100054 (2000-08-01), Conneely et al.
patent: 6111081 (2000-08-01), Conneely et al.
patent: 6228614 (2001-05-01), Conneely et al.
patent: 6277817 (2001-08-01), Kruzel et al.
patent: 6333311 (2001-12-01), Nuijens et al.
patent: 6399570 (2002-06-01), Mann
patent: 6410058 (2002-06-01), Gohlke et al.
patent: 6451344 (2002-09-01), Sotoyama et al.
patent: 6569831 (2003-05-01), Legrand et al.
patent: 6613741 (2003-09-01), Kruzel et al.
patent: 6635447 (2003-10-01), Conneely et al.
patent: 2002/0004073 (2002-01-01), Gohlke et al.
patent: 2002/0035061 (2002-03-01), Krieger et al.
patent: 2002/0046289 (2002-04-01), Conneely et al.
patent: 2002/0090660 (2002-07-01), Yi et al.
patent: 2002/0165128 (2002-11-01), Plaut et al.
patent: 2002/0192296 (2002-12-01), Gaull et al.
patent: 2003/0022821 (2003-01-01), Svenden et al.
patent: 2003/0190303 (2003-10-01), Kimber et al.
patent: 2004/0009895 (2004-01-01), Varadhachary et al.
patent: 2004/0009896 (2004-01-01), Glynn et al.
patent: 2004/0082504 (2004-04-01), Varadhachary et al.
patent: 2004/0142037 (2004-07-01), Engelmayer et al.
patent: 2004/0152624 (2004-08-01), Varadhachary et al.
patent: 2004/0157277 (2004-08-01), Clancy et al.
patent: 2004/0175388 (2004-09-01), Ding et al.
patent: 2005/0064546 (2005-03-01), Conneely et al.
patent: 2005/0075277 (2005-04-01), Varadhachary et al.
patent: 2006/0094082 (2006-05-01), Varadhachary et al.
patent: 2006/0134595 (2006-06-01), Rapp et al.
patent: 2006/0148029 (2006-07-01), Kim et al.
patent: 2006/0189790 (2006-08-01), Ropp et al.
patent: P000744901 (2001-12-01), None
patent: HEI 7(1995)-69915 (1995-03-01), None
patent: HEI 8 (1996)-73499 (1996-03-01), None
patent: WO 91 13629 (1991-09-01), None
patent: WO 95 19372 (1995-07-01), None
patent: 96/31537 (1995-10-01), None
patent: WO 96 06860 (1996-03-01), None
patent: 97/26908 (1997-07-01), None
patent: WO 99 14231 (1999-03-01), None
patent: WO-0203910 (2002-01-01), None
Elass-Rochard, E et al, Biochem. J., 1995, pp. 839-845, vol. 312, (abstract only).
Orlicek, SL e al, Septicemia and meningitis caused byHelicobacter cinaediin a neonate, Journal of Clinical microbiology, Mar. 1993, vol. 31(3), pp. 569-571.
Elass-Rochard et al (reference of record).
Giugliano, LG et al, J. Med. Microbiol., vol. 42, 1995, pgaes 3-9.
Sanchez et al.,Arch. Dis. child.67: 657-61 (1992).
Levay and Viljoen,Haematologica80: 252-67 (1995).
Lönnerdal and Iyer,Annu. Rev. Nutr.15: 93-110 (1995).
Ellison, R.T.,Adv. Exp. Med. Biol. 357:71-90 (1994).
Appelmelk et al.,Infect. Immun. 62:2628-2632 (1994).
Mann et al.,J. Biol. Chem. 269:23661-7 (1994).
Elass-Rochard et al.,Biochem. J. 312:839-845 (1995).
Bellamy et al.,Biochimica et Biophysica Acta 1121:130-136 (1992).
Bever et al.,Inflammation 13:309-16 (1989).
Levy et al.,Infect. Immun. 57:1632-4 (1989).
Boman et al., Eds., Antimicrobial Peptides, John Wiley & Sons Ltd., New York, NY (1994).
Hoffmann et al.,Curr. Opin. Immunol. 8:8-13 (1996).
Martin et al.,J. Leukoc. Biol. 58:128-36 (1995).
Ganz et al.,Curr. Opin. Hematol. 4:53-8 (1997).
Tang and Wong,J. Cell. B iochem. 33:53-63 (1987).
Briozzo et al.,Cancer Research 48:3688-3692 (1988).
Bazin et al., Inflammation, Biochemistry and Drug Interaction, A. Bertelli and J. C. Houck, Eds., Excerpta Medica., Amsterdam 1969), pp. 21-28.
Greenbaum, L.M., Proteases and Biological Control, E. Reich, D.B. Rifkin and E. Shaw, Eds. (Cold Spring Harbor Laboratory, New York, 1975), pp. 223-228.
Database WPI, Section Ch, Week 199635, Derwent Pub. Ltd., London, GB; AN 1996-350155 XP002145478 & JP 08 165248 A (Kuriiwa N), Jun. 25, 1996 abstract.
Database WPI, Section Ch, Week 199519 Derwent Pub. Ltd., London, GB; AN 1995-144726 XP002145479 & JP 07 069915 A (Snow Brand Milk Prod Co Ltd), Mar. 14, 1995 abstract & JP 07 069915 A Mar. 14, 1995.
Patent Abstracts of Japan, vol. 1996, No. 07, Jul. 31, 1996 & JP 08 073499 A (Snow Brand Milk Prod Co Ltd), Mar. 19, 1996 abstract.
U.S. Appl. No. 10/733,621, Dec. 11, 2003, Agennix Incorporated.
U.S. Appl. No. 10/732,429, Dec. 10, 2003, Agennix Incorporated.
U.S. Appl. No. 10/844,865, May 13, 2004, Agennix Incorporated.
U.S. Appl. No. 10/728,521, Dec. 5, 2003,Agennix Incorporated.
U.S. Appl. No. 10/862,213, Jun. 7, 2004, Agennix Incorporated.
U.S. Appl. No. 10/728,275, Dec. 4, 2003, Agennix Incorporated.

Affiliated with

Also associated with

Rating

Antimicrobial/endotoxin neutralizing polypeptide does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Antimicrobial/endotoxin neutralizing polypeptide, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Antimicrobial/endotoxin neutralizing polypeptide will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3806976