Antimicrobial disulfide prodrugs

Details Antimicrobial disulfide prodrugs Antimicrobial disulfide prodrugs

1982-06-08

1984-01-24

Phillips, Delbert R.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424177, C07C10352, A61K 3700

Patent

active

044275820

ABSTRACT:
A series of prodrugs is described which have improved antimicrobial activity and physico-chemical properties. The structures of the biologically active ingredients are characterized by having a selected oligopeptide backbone attached, via the .alpha.-carbon of an L-alanyl unit thereof, by means of a disulfide link to the residue of an antimicrobial mercaptan.

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