Antimicrobial dihydrothiazine and dihydrothiopyran...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C514S380000, C514S432000, C548S229000, C548S243000, C548S240000, C249S028000, C544S056000

Reexamination Certificate

active

06884813

ABSTRACT:
The present invention provides a compound of formula Ior a pharmaceutically acceptable salt thereof wherein A is a structure i, ii, iii, or ivX is CR7; Y is —S(═O)n—, —S(═NR8)—, or —S(═NR8)(═O)—; Z is —NHC(═O)R1, —NHC(═S)R1, —NR-het1, —O-het1, —S-het1, or -het2; and n is independently 0, 1, or 2. The compounds of formula I are useful as antimicrobials against a number of human and veterinary pathogens.

REFERENCES:
patent: 5688712 (1997-11-01), Ema et al.
patent: 5968962 (1999-10-01), Thomas et al.
patent: 5981528 (1999-11-01), Gravestock
patent: 20010041728 (2001-11-01), Hester, Jr. et al.
patent: WO 9507271 (1995-03-01), None
patent: WO 0281470 (2002-10-01), None
Barbachyn, et al, J. Med. Chem. 1996, 39, 680-5.

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