Antimicrobial compound and compositions particularly effective a

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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A61K 31435

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active

049652729

ABSTRACT:
The use of the naturally occurring and readily synthesized alkaloid compound eupolauridine as an antimicrobial agent and particularly against Candida albicans organism .

REFERENCES:
Rao et al., "Sampangine, A New Alkaloid . . . ", Journal of Nat. Prod., vol. 49, No. 2, pp. 346-347 (1986).
Taylor, "Constituents of Eupometta Species", Austrlian Journ. Chem., 37, pp. 1095-1104 (1984).
Read et al., "Constit. of Eupometia Species", Austrlian Journ. Chem., 32, pp. 2317-2321 (1979).
Bowden et al., "Constit. of Eupomatia Species", Australian Journ. Chem. 29, pp. 2681-2702 (1975).
(I) Leboeuf et al., "Alkaloids of Annonaceae", Chem. Abs., vol. 87(3), entry #87:235826 (1977).
Hufford et al., "Anticandidal Activity of Eupolauridine", Journ. Nat. Prod., vol. 50, No. 5, pp. 961-964 (1987).
Waterman et al., "Chem. of Annonacease", Chem. Abs., vol. 103 (3), entry No. 103:19823n (1985).
Tadic et al., "Kinabaline . . . ", Bio. Abs., vol. 83, No. 9, entry #89433 (1987).
Leboeuf etal. (II), "Alkaloids of Annonaceae", Chem. Abs., vol. 83, No. 13, entry #83:111113x (1975).

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