Antimicrobial compositions

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Conjugate or complex

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424258, A61K 3578, A61K 3147

Patent

active

040937178

ABSTRACT:
Antimicrobial compositions useful in mammal. An extract of the heartwood of Liriodendron tulipifera L., provides components and derivatives thereof useful as antimicrobial agents; antimicrobial compositions comprising liriodenine, dehydroglaucine liriodenine methiodide and oxoglaucine methiodide compounds of and derivatives and mixtures thereof of alkaloids isolated from the extract of the heartwood of Liriodendron tulipifera L. The antimicrobial compositions being particularly useful against Gram positive bacteria, acid fast bacteria and fungi and yeast.

REFERENCES:
patent: 67763 (1867-08-01), Hoeing
patent: 186141 (1877-01-01), Lipscomb
patent: 280281 (1883-06-01), Atkins
patent: 440998 (1890-11-01), Farrell
Journal Organic Chemistry, vol. 25: pp. 1389-1390 (Aug. 1960) and vol. 26: pp. 4143-4144 (Oct. 1960).
J. Pharm. Soc. Japan, vol. 82: pp. 616-617 & 1199-1202 (1962).
J. Pharm. Soc. Japan, vol. 86: pp. 124-128 (1966).
Hufford et al, J. Pharm. Sci., vol. 64, No. 5, May 1975, pp. 789-792.

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