Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1998-08-24
2000-11-21
Geist, Gary
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514206, 540222, 540225, 540302, 540310, A61K 31545, C07D50100, C07D48700, C07D49900
Patent
active
061503509
ABSTRACT:
The invention relates to antimicrobial compositions comprising a combination of (1) a therapeutically effective amount of a compound of formula I ##STR1## with (2) a second ingredient selected from carbapenem antibiotics or with .beta.-lactamase inhibitors, to the use of the compositions for producing a medicament for the treatment and prophylaxis of infectious diseases, including MRSA infections, and to pharmaceutical compositions containing the combination.
REFERENCES:
patent: 5464616 (1995-11-01), Noguchi et al.
patent: 5644053 (1997-07-01), Hubschwerlen et al.
Derwent Abstract No. JP 2279627.
Hohl et al., Abstracts of the Interscience Conference on Antimicrobial Agents and Chemotherapy, vol. 36, p. 125 (1996).
Jones et al., Diagnostic Microbiology and Infectious Disease, vol. 32, No. 2, p. 85-94 (1998).
Angehrn Peter
Heinze-Krauss Ingrid
Page Malcolm
Richter Hans G. F.
Ebel Eileen M.
Geist Gary
Hoffman-La Roche Inc.
Johnston George W.
Rocha-Tramaloni Patricia S.
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