Prosthesis (i.e. – artificial body members) – parts thereof – or ai – Miscellaneous
Patent
1987-08-31
1989-07-11
Apley, Richard J.
Prosthesis (i.e., artificial body members), parts thereof, or ai
Miscellaneous
623 11, 128DIG21, 424425, 427 2, 514179, 6048901, A61F 254
Patent
active
048468444
ABSTRACT:
Uniform adherent coatings of antimicrobial agents are applied to the surface of implants by applying a film of silicone oil to the surface of the implant and contacting the film-bearing surface with antimicrobial agents in a film-adherent form. A durable antimicrobial coating is formed. The coated implants can be packaged using mechanized implant handling equipment without significant loss of the antimicrobial coating. In a preferred embodiment a controlled-release implant for administering an anabolic agent is coated with a durable nonvulcanizing silicone fluid plus oxytetracycline hydrochloride coating which does not interfere with diffusion of the anabolic agent from the implant.
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De Leon Jose
Ferguson Thomas H.
Skinner, Jr. Daniel S.
Apley Richard J.
Eli Lilly and Company
Prebilic Paul
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