Antimicrobial cationic peptides

Details Antimicrobial cationic peptides Antimicrobial cationic peptides

2005-06-14

2005-06-14

Weber, Jon (Department: 1653)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

C514S013800, C530S324000, C530S325000, C530S326000, C530S334000, C435S069100, C424S009100

Reexamination Certificate

active

06906035

ABSTRACT:
A novel class of cationic peptides having antimicrobial activity is provided. Examples of such peptides include NH2-KWKSFIKKLTTAVKKVLTTGLPALIS-COOH (SEQ ID NO:1) and NH2-KWKSFIKKLTSAAKKVVTTAKPLISS-COOH (SEQ ID NO:2). Also provided are methods for inhibiting the growth of bacteria utilizing the peptides of the invention. The peptides are particularly useful for inhibiting endotoxemia in a subject.

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