Antimicrobial cationic peptides

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

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530324, 530326, 514 12, 435 691, C07H 2104

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active

060404353

ABSTRACT:
A novel class of cationic peptides having antimicrobial activity is provided. Examples of such peptides include

REFERENCES:
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patent: 5877274 (1999-03-01), Hancock et al.
Piers et al. (1993) Gene, vol. 134, pp. 7-13, 1993.
K.L. Piers et al., "The Interaction of a recombinant cecropin/melitten hybrid peptide wth the outer membrane of Pseudomonas aeruginosa", Molecular Microbiology, vol. 12, No. 6, pp. 951-958.
J.W. Larrick, et al., "A Novel Granulocyte-Derived Peptide with Lipopolysaccharide-Neutralizing Activity", Journal of Immunological Methods, vol. 152, New York, US, PP. 231-240 (1994).
Hirata et al., "Structure and Functions of Endotoxin-Binding Peptides Derived from CAP18", Bacterial Endotoxins: Lipopolysaccharides from Genes to Therapy, pp. 317-326, 1995

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