Antimicrobial agents

Details Antimicrobial agents Antimicrobial agents

2011-03-29

2011-03-29

Russel, Jeffrey E (Department: 1654)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

C426S335000, C514S014800, C514S015800, C514S016700, C514S017400, C514S018700, C530S326000, C530S327000, C530S328000, C530S329000, C530S330000, C530S331000, C530S332000

Reexamination Certificate

active

07915223

ABSTRACT:
A novel class of antimicrobial polymeric agents, which include a plurality of amino acid residues, such as positively charged amino acid residues, and at least one hydrophobic residue linking therebetween, such as an omega-amino-fatty acid residue, designed to exert antimicrobial activity while being stable, non-toxic and avoiding development of resistance thereto, and a process of preparing same, are disclosed. Further disclosed are pharmaceutical compositions containing same and a method of treating medical conditions associated with pathological microorganisms, a medical device, an imaging probe and a food preservative utilizing same. Further disclosed are conjugates of an amino acid residue and a hydrophobic moiety residue and a process of preparing same.

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