Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – N-c doai
Reexamination Certificate
2006-05-03
2011-12-13
Wang, Shengjun (Department: 1627)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
N-c doai
C514S602000, C514S634000, C514S352000, C514S252010, C546S304000, C558S242000, C564S080000, C564S230000
Reexamination Certificate
active
08076370
ABSTRACT:
Provided herein are substituted aromatic compounds, which are tRNA synthetase inhibitors, and hence can be used as antimicrobial agents. Compounds described herein can be used for the treatment or prevention of a condition caused by or contributed to by gram positive, gram negative, anaerobic bacteria or fungal organisms, more particularly against bacterium, for example,Staphylococci, Enterococci, Streptococci, Haemophilus, Moraxalla, Escherichia, Chlamydia, Mycoplasm, Legionella, Mycobacterium, Helicobacter, Clostridium, Bacteroides, Corynebacterium, Bacillusor Enterobactericeae, and fungal organisms, for example,Aspergillus, Blastomyces, Candida, Coccidiodes, Cryptococcus, Epidermophyton, Hendersonula, Histoplasma, Microsporum, Paecilomyces, Paracoccidiodes, Pneumocystis, Trichophyton, orTrichosporium. Processes for the preparation of these compounds, pharmaceutical compositions thereof, and methods of treating microbial infections are also provided.
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Ahmed Shahadat
Arora Jasbir Singh
Bandyopadhyay Anish
Das Biswajit
Ghosh Soma
Ranbaxy Laboratories Limited
Wang Shengjun
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