Antimicrobial agent

Details Antimicrobial agent Antimicrobial agent

2002-08-29

2011-12-20

Flood, Michele (Department: 1655)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Wearing apparel, fabric, or cloth

C424S776000, C424S750000, C424S757000, C424S727000, C530S358000

Reexamination Certificate

active

08080258

ABSTRACT:
A proteineous component isolated from plant chromatin, after dissociation of the same, as an antimicrobial agent, the proteineous component having an apparent molecular weight between 10 and 20 kD. The proteineous plant component is produced by means of a method comprising the steps of homogenizing a plant material in order to expose its plant chromatin, dissociating the plant chromatin with a dissociating agent under hydrophobic conditions, and separating the dissociated plant chromatin into individual fractions, one comprising the proteineous plant component, by means of a hydrophobic interaction separation procedure.

REFERENCES:
patent: 5573801 (1996-11-01), Wilhoit
patent: 6350738 (2002-02-01), Savage et al.
patent: 2001/0010909 (2001-08-01), Cahoon et al.
patent: 61-30526 (1986-02-01), None
patent: 61-030526 (1986-02-01), None
patent: 63-179899 (1987-05-01), None
patent: 62-116600 (1988-07-01), None
patent: 2000-7699 (2000-01-01), None
patent: WO 01/10901 (2001-02-01), None
patent: WO 01/010901 (2001-02-01), None
patent: WO 0110901 (2001-02-01), None
Gotay, IC et al. Proc. Soc. Exp. Biol Med. (1966); 122(4): 1115-1116. Differentiation of atypicalPseudomonas aeruginosafromAlcaligenes fecalisusing a histone-like fraction from Carica papaya seeds.
Hadwiger, LA et al. Phytopathology (1977); 67(6): 755-758. An evaluation of pea histones as disease resistance factors.
Fambrough, DM et al. Biochemistry (1966): 5(8):n2563-70. On the similarity of plant and animal histones.
Singh, NP et al. Plant Molecular Biology (1992): 33(3): 124-128. Nuclear proteins and chromatin structure of pea root nodule.
Mitheiux, G et al. Biochemica et Biophysica Acta (1984); 781(3): 286-293. Study of chromatin domain different from bulk chromatin in barley Hordium-vulgare nuclei.
Hoffmann, KL et al. J of Food Protection (Jun. 2001); 64(6): 885-889. Antimicrobial effects of corn zein films impregnated with nisin, lauric acid and EDTA.
Esen, A. Plant Physiol (1986); 80: 623-627. Separation of alcohol-soluble proteins (zeins) from maize into three fractions by differential solubiltiy.
Viotti, A et al. Molec Gen Genet. (1080): 178: 35-41. Chromosomal localization of zein genes by in situ hybridization in Zea mays.
Spiker, S. “An Evolutionary Comparison of Plant Histones,” Biochimica et Biophysica Acta (1975) 400: 461-467.
Hirsch, James G. “Bactericidal Action of Histone,” J. Exp. Med. (1958) 108(6): 925-944.
Hancock, R. E. W. And Chapple, D.S. “Minireview: Peptide Antibiotics,” Antimicrobial Agents and Chemotherapy (1999) 43(6): 1317-1323.
Hancock, R.E.W. “Peptide Antibiotics,” Lancet (1997) 349: 418-422.
Cammue, B.P. et al., “Gene-encoded Antimicrobial Peptides from Plants”, Ciba Foundation Symposium, 1994, vol. 186 pp. 91-106.
Esen, A., “Separation of alcohol-soluble proteins (zeins) from maize into three fractions by differential solubility”, Plant Physiol, 1986, vol. 80, pp. 623-627.
Fambrough, D.M. and Bonner, J., “On the Similarity of Plant and Animal Histones”, Biochemistry, 1966, 5(8):2563-2570.
Gotay, I.C., “Differentiation of AtypicalPseudomonas aeruginosafromAlcaligenes fecalisUsing a Histone-Like Fraction fromCarica papayaSeeds”, Proc. Soc. Exp. Biol. Med., 1966, 122(4):1115-1116.
Hadwiger, L..A., “An Evaluation of Pea Histones as Disease Resistance Factors”, Phytopathology, 1977, 67(6):755-758.
Hoffman, K.L. et al., “Antimicrobial Effects of Corn Zein Films Impregnated with Nisin, Lauric Acid, and EDTA”, Journal of Food Protection, 2001, 64(6):885-889.
Viotti, A. et al., “Chromosomal Localization of Zein Genes by in situ Hybridization in Zea mays”, Moled. Gen. Genet., 1980, 178:35-41.
Ye, X.Y. and Ng, T.B., “Mungin, a Novel Cyclophilin-like Antifungal Protein from the Mung Bean”, Biochemical and Biophysical Research Communications, 2000, 276(3):1111-1115.
X.Y. Ye et al., “Mungin, a Novel Cyclophilin-Like Antifungal Protein From the Mung Bean,” Department of Biochemistry, Chinese University of Hong Kong, Jun. 13, 2000, p. 2.

Affiliated with

Also associated with

Rating

Antimicrobial agent does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Antimicrobial agent, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Antimicrobial agent will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4258815