Antimicrobial 1-thienyl-4-oxoquinoline-3-carboxylic acids

Details Antimicrobial 1-thienyl-4-oxoquinoline-3-carboxylic acids Antimicrobial 1-thienyl-4-oxoquinoline-3-carboxylic acids

1986-11-13

1988-11-22

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546156, 548550, 548551, 548566, 548568, 560 9, 560 51, 560 53, C07D40914, A61K 3147

Patent

active

047866497

ABSTRACT:
Novel 1-thienyl-4-oxoquinoline-3-carboxylic acid compounds of the formula ##STR1## wherein R.sup.1 is an amino (lower) alkyl, R.sup.2 is thienyl, and X is a halogen atom, and a pharmaceutically acceptable salt thereof, said compounds having excellent antimicrobial activity and hence being useful as an antimicrobial agent, and a pharmaceutical composition comprising as an active ingredient said 1-thienyl-4-oxoquinoline-3-carboxylic acid compounds or a pharmaceutically acceptable salt thereof in admixture with a pharmaceutically acceptable diluent or carrier.

REFERENCES:
patent: 4616019 (1986-10-01), Chu, II
patent: 4617308 (1986-10-01), Mich et al.
patent: 4730000 (1988-03-01), Chu
Chemical Abstracts, vol. 106, 119709k for Japan Pat. No. 61,251,667 (8/11/86).

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