Antimicrobial 1-substituted phenyl-4-oxoquinoline-3-carboxylic a

Details Antimicrobial 1-substituted phenyl-4-oxoquinoline-3-carboxylic a Antimicrobial 1-substituted phenyl-4-oxoquinoline-3-carboxylic a

1985-08-28

1987-08-04

Rosen, Sam

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514254, 544349, 544363, 546156, A61K 3140, A61K 3147, C07D40114

Patent

active

046846484

ABSTRACT:
Novel 1-substituted phenyl-4-oxoquinoline-3-carboxylic acid compounds of the formula: ##STR1## wherein R is hydrogen atom or fluorine atom, R.degree. is hydroxy, fluorine atom or an alkanoyloxy having 1 to 6 carbon atoms, and X.sup.1 is hydrogen atom or fluorine atom, and a pharmaceutically acceptable salt thereof, said compounds having excellent antimicrobial activity and hence being useful as an antimicrobial agent, and a pharmaceutical composition comprising as an active ingredient said 1-substituted phenyl-4-oxoquinoline-3-carboxylic acid compounds or a pharmaceutically acceptable salt thereof in admixture with a pharmaceutically acceptable diluent or carrier.

REFERENCES:
patent: 4398029 (1983-08-01), Irikura et al.
patent: 4571396 (1986-02-01), Hutt

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