Antimicrobial 1,3-disubstituted/imidazolium salts

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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5142358, 514252, 514313, 514316, 514326, 514341, 514395, 514398, 544 585, 544 60, 544139, 544370, 546159, 546187, 546210, 546278, 548327, 548329, 548337, A61K 31535, C07D4136

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048143324

ABSTRACT:
The imidazolium compounds of the formula ##STR1## wherein the various substituents are defined hereinbelow and their pharmaceutically acceptable acid addition salts, which possess valuable pharmacological properties are described. In particular, they possess antibacterial, antimycotic, protozoacidal and/or anthelmintic properties and are especially active against parasitic protozoa and worms. The compounds of formula I can be prepared according to known methods.

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E. Karpitschka, Innsbruck University Dissertation, 1981.
R. Mussner, Innsbruck University Dissertation, 1982.
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Chemical Abstracts 101, 2110040e (1984) [Ukhin L., et al, ZH. Obshch. Kmim. 1984, 54(7), 1678-8].

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