Antimetastatic peptides with laminin activity

Details Antimetastatic peptides with laminin activity Antimetastatic peptides with laminin activity

1991-10-29

1992-12-29

Moezie, F. T.

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

25 or more amino acid residues in defined sequence

530325, 435 691, 930260, 930DIG821, 930DIG820, 930DIG800, C07K 710

Patent

active

051752514

ABSTRACT:
Human laminin B.sub.1 peptides have been produced. The invention provides novel peptides which contain substantial amino acid sequence similarity to amino acids 897 to 936 in the human sequence. These peptides have been found to have enhanced antimetastatic activity.

REFERENCES:
patent: 4497799 (1985-02-01), Yoshizumi et al.
patent: 4565789 (1986-01-01), Liotta et al.
patent: 4578079 (1986-03-01), Ruoslahti et al.
patent: 4605413 (1986-08-01), Urry et al.
patent: 4614517 (1986-09-01), Ruoslahti et al.
patent: 4642293 (1987-02-01), Chung
patent: 4714683 (1987-12-01), Shoyab et al.
Charonis et al., J. Cell. Biol., vol. 107(3), pp. 1253-1260, (1988), [Chem. Abs., vol. 109 (25), 225046p].
Durkin et al., (1988) Biochem 27(14):5198-5204.
Barlow et al., (1985) Chemical Abstracts 102:168.
Conlon et al., (1986) Chemical Abstracts 105:392.
Sasaki et al., (1988) J Biol Chem 263 (23):16536-16544.
Peter et al., (1989) J Mol Biol 208:393-404.
Martin, (1987) Ann Rev Cell Biol 3:57-85.
Martin et al., (1987) Federation Meetings, Minisymposium 7:New Approaches to Analyzing Extracellular Matrix Function, Abstract No. 504.
Liotta et al., (1986) Cancer Res 46:1-7.
Terranova et al., (1983) Proc Natl Acad Sci USA 80:444-448.
Terranova et al., (1982) Cancer Res 42:2265-2269.
Vlodavsky and Gospodarowicz, (1981) Natura 289:304-306.
Rao et al., (1983) Biochem Biophys Res Comm 111(3):804-808.
Charonis et al., (1985) J Cell Biol 100:1848-1853.
Barsky et al., (1984) J Clin Invest 74:843-848.
Pikkaraimen et al., (1989) J Biol Chem 262:10454-10462.
Sasaki et al., (1987) Proc Natl Acad Sci USA 84:935-939.
Graf et al., (1987) Cell 48:989-996.
Graf et al., (1987) Biochem 26:6896-6900.
Iwamoto et al., (1988) J Cell Physiol 134:287-291.
Yamada and Kennedy, (1987) J Cell Physiol 130:21-28.
Skubitz et al., (1987) Exp Cell Res 173:349-369.
McCarthy et al., (1988) J Natl Cancer Inst 80(2):108-115.

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