Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2006-03-03
2010-02-23
Davis, Zinna N (Department: 1625)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S277000, C546S290000, C546S301000, C546S339000
Reexamination Certificate
active
07666883
ABSTRACT:
The present invention is directed towards the synthesis of novel and new chloropyridine skeleton based compounds and these are Bayllis Hillman adducts having a remarkable in vitro anti-malarial activity. These compounds have been found to possess anti-malarial activity against chloroquine sensitive and chloroquine resistantPlasmodium falciparum. The anti-malarial compounds of the present invention inhibit the mature schizonts in vitro.
REFERENCES:
patent: 6479660 (2002-11-01), Ugwuegbulam et al.
Narender et al, Tetrahedron, vol. 62, Issue 5, Jan. 30, 2006, pp. 954-959.
Segheraert. et al. J.Med.Chem. 46, 2003, pp. 542-547.
Gangadasu Banda
Kumar Sriramoju Bharat
Narender Puli
Ramesh Chilukuri
Rao Janaswamy Madhusudhan
Council of Scientific and Industrial Research
Davis Zinna N
DLA Piper (LLP) US
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