Antimalaria and antibabesiosis agents and pharmaceutical composi

Details Antimalaria and antibabesiosis agents and pharmaceutical composi Antimalaria and antibabesiosis agents and pharmaceutical composi

1999-02-01

2000-08-01

Boykin, Terressa M.

Drug, bio-affecting and body treating compositions

Malaria

A01N 4340

Patent

active

060967889

ABSTRACT:
The invention concerns pharmaceutical compositions with antimalaria and antibabesiosis activity, the active substances of these compositions and their use for formulating antimalaria drugs.

REFERENCES:
M.L. Ancelin et al., "Inhibitors of choline transport into Plasmedium-infected erythrocytes are effective antiplasmodial compounds in vitro", pp. 4068-4071, Biochemical Pharmacology, vol. 34, No. 22, Jun. 27, 1985.
M.L. Ancelin et al., "Quaternary Ammonium Compounds Efficiently Inhibit Plasmodium falciparum Growth In Vitro by Impairment of Choline Transport", pp. 814-820, Antimicrobial Agents and Chemotherapy, vol. 29, No. 5, May 1986.
J.T. Holden et al., "Inhibition of High-Affinity Choline Transport in Rat Striatal Synaptosomes by Alkyl Bisquaternary Ammonium Compounds", pp. 19-27, Molecular Pharmacology, vol. 11, No. 1, Jul. 30, 1974.

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