Antiinflammatory PLA.sub.2 inhibitors

Details Antiinflammatory PLA.sub.2 inhibitors Antiinflammatory PLA.sub.2 inhibitors

1989-07-28

1991-08-13

Schenkman, Leonard

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Nitrogen containing other than solely as a nitrogen in an...

514654, 564367, A61K 31135, C07C21100

Patent

active

050397060

ABSTRACT:
The invention relates to benzylamine phosphilipase A.sub.2 inhibitors, pharmaceutical compositions containing them, and methods of treating phospholipase A.sub.2 -mediated conditions in mammals by administration of a therapeutically effective amount of such a benzylamine phospholipase A.sub.2 inhibitor.

REFERENCES:
patent: 3979444 (1976-09-01), Ledniger
patent: 4239780 (1980-12-01), Wallach
Wallach et al., Biochemical Pharmacology, 30, 1315 (1981).

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