Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Cyclopentanohydrophenanthrene ring system doai
Patent
1995-06-02
1998-09-01
Prior, Kimberly J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Cyclopentanohydrophenanthrene ring system doai
514174, 514179, 514180, 540 67, 552525, C07J 7100, C07J 7500, A61K 3158
Patent
active
058011650
ABSTRACT:
Compounds of formula I ##STR1## where R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6, n, and are as defined herein, their use as antiinflammatory, immunosuppressive, and antiallergic agents, pharmaceutical compositions comprising them, and methods for their preparation comprising irradiating compounds of formula II ##STR2## under an inert atmosphere, in the presence or absence of a compound of formula R.sub.3 --S--S(O).sub.m --R.sub.8, where R.sub.7, R.sub.8, and m are as defined herein, and methods for their preparation comprising oxidizing, reducing, halogenating, or alkylating compounds of formula I are disclosed.
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Ashton Michael John
Karlsson Sven Jan-Anders
Vacher Bernard Yvon Jack
Withnall Michael Thomas
Darkes Paul R.
Martin Michael B.
Parker III Raymond S.
Prior Kimberly J.
Rhone-Poulenc Rorer Limited
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