Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...
Patent
1976-01-19
1977-08-09
Friedman, Stanley J.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Parasitic organism or component thereof or substance...
A61K 31425
Patent
active
040411672
ABSTRACT:
Certain imidazothiazoles and thiazolopyrimidines have been found to prevent and inhibit the formation of granuloma tissue in animals. This result is accomplished by administering to the animal subject a therapeutically effective amount of a compound having the formula: ##STR1## wherein R is hydrogen or methyl, R' is hydrogen, lower alkyl or thioalkyl, carboxy methyl, or phenyl; R" is lower alkyl, 2-benzofuranyl, naphthyl, phenyl, or mono- or disubstituted phenyl. The hydrated precursors of certain of these compounds as well as the acid addition and quaternary salts of both the compounds and their hydrated precursors may be employed.
REFERENCES:
Chem. Abst., 74-13059D (1971).
Chem. Abst., 75-63677V (1971).
Chem. Abst., 76-113162S (1972).
Chem. Abst., 76-41919U (1972).
Inpharma, 20th, Mar. 1976, p. 19 (ADIS Press).
Merck Index, 9th Ed., p. 8949.
Ariyan Zaven S.
Moser Robert E.
Powers Larry J.
Diamond Shamrock Corporation
Friedman Stanley J.
Melton Stuart L.
Tinkler Timothy E.
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