Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1992-02-18
1993-10-26
Springer, David B.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
546165, C07D 2514, A61K 3147
Patent
active
052567893
ABSTRACT:
Compounds having the structure ##STR1## wherein X is nitrogen, oxygen, sulfur or a bond and Z is oxygen or sulfur have been synthesized. These compounds are lipoxygenase inhibitors and are useful as the active agent in pharmaceutical compositions for treating inflammatory conditions in humans and other mammals for which lipoxygenase activity has been implicated.
Ikeda Takafumi
Nakane Masami
Stevens Rodney W.
Wakabayashi Hiroaki
Benson Gregg C.
McFarlin D. Stuart
Pfizer Inc.
Richardson Peter C.
Springer David B.
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