Antiinflammatory and/or analgesic 1-alkyl-4,5-diaryl-2-fluoroalk

Details Antiinflammatory and/or analgesic 1-alkyl-4,5-diaryl-2-fluoroalk Antiinflammatory and/or analgesic 1-alkyl-4,5-diaryl-2-fluoroalk

1982-05-10

1984-10-16

Rollins, Alton D.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Fungus, except allergen, or component thereof or substance...

424263, 548560, 546281, C07D20732, C01D40304, A61K 3144, A61K 3140

Patent

active

044774630

ABSTRACT:
Antiinflammatory and/or analgesic 1-alkyl-4,5-diaryl-2-fluoroalkyl-1H-pyrroles, such as 4,5-bis(4-methoxyphenyl)-1-methyl-2-trifluoromethyl-1H-pyrrole, useful for treating arthritis and related diseases and/or relieving pain.

REFERENCES:
patent: 3707475 (1972-12-01), Lombardino
patent: 3709906 (1973-01-01), Yoshida et al.
patent: 3758515 (1969-07-01), Archibald et al.
patent: 4168315 (1979-09-01), Rynbrandt et al.
patent: 4267189 (1981-05-01), Cherkofsky
patent: 4318917 (1982-03-01), Cherkofsky et al.
patent: 4335136 (1982-06-01), Cherkofsky
Jones et al, The Chem. of Pyrroles, Academic Press, N.Y. N.Y., pp. 144-146 (1977).
Cantacuzene, et al., "Condensation of Perfluoroalkyl Iodides with Unsaturated Nitrogen Compounds", J. Chem. Soc. I, 12, pp. 365-1371 (1977).

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