Antiinflammatory 4,5-diaryl-.alpha.-(polyhalomethyl)-2-thiophene

Details Antiinflammatory 4,5-diaryl-.alpha.-(polyhalomethyl)-2-thiophene Antiinflammatory 4,5-diaryl-.alpha.-(polyhalomethyl)-2-thiophene

1981-08-27

1983-04-26

Siegel, Alan

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Allergen or component thereof

424263, 549 75, 549 78, 549 79, 546256, 546268, A61K 3138, A61K 3144, C07D33316, C07D40100

Patent

active

043813119

ABSTRACT:
4,5-Diaryl-.alpha.-(polyhalomethyl)-2-thiophenemethanols such as 4-(4-methoxyphenyl)-5-(4-methylthiophenyl)-.alpha.,.alpha.-bis(trifluorome thyl)-2-thiophenemethanol useful for treating arthritis and/or alleviating pain.

REFERENCES:
patent: 3197480 (1965-07-01), England
patent: 3531497 (1970-09-01), Youngdale
patent: 3644399 (1972-02-01), Brown
patent: 3652575 (1972-03-01), Hutton et al.
patent: 3721681 (1973-03-01), Hutton et al.
patent: 4174405 (1979-11-01), Relyea
Reinecke, et al., J. Chem. Soc., Chem. Commun. 585, (1980).

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