Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...
Patent
1981-05-22
1983-10-25
Schwartz, Richard A.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Parasitic organism or component thereof or substance...
42424852, 42424854, 42424856, 42424858, 424250, 424267, 424273R, 542457, 542458, 544139, 544370, 546199, 548326, A61K 31415, C07D23502, C07D23518
Patent
active
044119070
ABSTRACT:
3H-naphth[1,2-d]imidazole derivatives of formula ##STR1## wherein R stands for hydrogen, methyl or ethyl, R.sub.1 represents hydrogen, methyl or ethyl, R.sub.2 represents hydrogen, methyl, ethyl, phenyl or substituted phenyl, the symbol R.sub.3 stands for a phenyl radical optionally substituted and R.sub.4 and R.sub.5, each independently, may represent hydrogen, halogen, (C.sub.1 -C.sub.4)alkyl, (C.sub.1 -C.sub.4)alkylthio, (C.sub.1 -C.sub.4)alkoxy or halo-(C.sub.1 -C.sub.4)alkoxy, are described. Also described is the process for preparing the novel compounds, their use as antiinflammatory agents and the pharmaceutical compositions containing them.
REFERENCES:
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March, J., Advanced Organic Chemistry, McGraw Hill, New York, 1968, pp. 343-344.
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Roberts, J., et al., Basic Principles of Organic Chemistry, W. A. Benjamin, New York, 1965, p. 486.
Gruppo Lepetit S.p.A.
McDonald Raymond A.
Schwartz Richard A.
Stein William J.
Street Gary D.
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