Antihypotensive tetrahydro-1H-pyrazolo[5,1-a]isoindoles

Details Antihypotensive tetrahydro-1H-pyrazolo[5,1-a]isoindoles Antihypotensive tetrahydro-1H-pyrazolo[5,1-a]isoindoles

1984-04-17

1986-02-04

Schwartz, Richard A.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514403, 548348, 548369, A61K 31415, C07D48704

Patent

active

045686882

ABSTRACT:
New substituted tetrahydro-1H-pyrazolo[5,1-a]isoindoles of the formula I ##STR1## in which R.sup.1 denotes a hydrogen or halogen atom or an alkoxy group having 1 to 4 carbon atoms, R.sup.2, R.sup.3 and R.sup.4, which can be identical or different, denote a hydrogen atom or an alkyl group having 1 to 4 carbon atoms, or R.sup.2 and R.sup.3 together denote the ethylene group, and X denotes a nitrogen atom or a methine group, and their acid addition salts have a long-lasting hypertensive effect and can be used as anti-hypotensives.

REFERENCES:
patent: 4075342 (1978-02-01), Omodei-Sale et al.
CAS Registry Handbook for 1965-1971, Published 1974, Chemical Abstracts Service, Columbus, OH, p. 3100R.

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