Antihyperthermic use for prostaglandins

Details Antihyperthermic use for prostaglandins Antihyperthermic use for prostaglandins

1977-07-18

1978-09-19

Rosen, Sam

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Recombinant or stably-transformed bacterium encoding one or...

424305, A61K 3119, A61K 31215

Patent

active

041155866

ABSTRACT:
The present invention provides a method whereby pyrogen-induced, prostaglandin-induced and idiopathic fever is alleviated by systemic administration of a hypothermic prostaglandin.
The hypothermic prostaglandins of the present invention are .omega.-aryl-PGF-type compounds, e.g., 15-methyl-17-phenyl-.omega.-trinor-PGF.sub.2.alpha. and 16-phenoxy-.omega.-tetranor-PGF.sub.2.alpha..

REFERENCES:
upjohn Prostaglandin Bibliography, Nov. 6, 1969 & Supplement pp. 1970-22 & 1972-42.

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