Antihypertensive sulfonanilides

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...

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564 99, A61K 3118, C07C14374

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active

051029146

ABSTRACT:
The present invention is concerned with compounds of formula (I) ##STR1## wherein R.sub.1 is hydrogen;

REFERENCES:
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Aldrichimica Acta, vol. 20, No. 1, 1987--I. Chiral Reducing Agents.
JAMA, Dec. 11, 1967, vol. 202, No. 11, pp. 116-112, Effects of Treatment on Morbidity in Hypertension, Results in Patients with Diastolic Blood Pressure Averaging 115 through 129 mm Hg.
JAMA, Aug. 17, 1970, vol. 213, No. 7, pp. 1143-1152, Effects of Treatment on Morbidity in Hypertension, II. Results in Patients with Diastolic Blood Pressure Averaging 90 through 114 mm Hg.
Current Therapy, 1981, Hypertension, pp. 219-223.
Temple, et al., Journal of Medicinal Chemistry, 1976, vol. 19, No. 5, pp. 626-633, Adrenergic Sulfonanilides. 4, Centrally Active .beta.-Adrenergic Agonists.

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