Antihypertensive substituted imidazole derivatives

Details Antihypertensive substituted imidazole derivatives Antihypertensive substituted imidazole derivatives

1982-07-07

1985-10-01

Schwartz, Richard A.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514397, 514400, 548335, 548336, 548342, A61K 31415, C07D23356, C07D23364

Patent

active

045446644

ABSTRACT:
The invention provides novel compounds of the formula: ##STR1## wherein the various substituents are defined herein below. Processes for the preparation of these compounds are described, as are novel pharmaceutical compositions comprising at least one of the compounds of their salts. The compounds and their non-toxic salts exhibit valuable pharmacological activity and are useful in the treatment of mammals, especially as antihypertensive agents. Furthermore, some of the compounds have proved to possess antithrombotic and diuretic activity. Antimycotic and antifungal properties have also been found.

REFERENCES:
patent: 2946804 (1960-07-01), Zaugg et al.
patent: 4333947 (1982-06-01), Karjalainen et al.
patent: 4443466 (1984-04-01), Karjalainen et al.
Kelley, J., et al., J. Pharm. Sci., 70(3), 341-343, (1981).

Affiliated with

Also associated with

Rating

Antihypertensive substituted imidazole derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Antihypertensive substituted imidazole derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Antihypertensive substituted imidazole derivatives will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1442753