Antihypertensive pyridines and compositions

Details Antihypertensive pyridines and compositions Antihypertensive pyridines and compositions

1980-04-11

1981-03-24

Randolph, John D.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

42424851, 42424852, 42424854, 42424855, 544122, 544128, 544131, A61K 31535, C07D29514

Patent

active

042580420

ABSTRACT:
Antihypertensive compounds of the formula ##STR1## wherein R.sub.5 is H, alkyl, aryl, halo, lower alkoxy, nitro amino, alkylmercapto, cyano, carboxy, carbalkoxy, sulfamyl, trifluoromethyl, hydroxy, acyloxy, methanesulfonyl, alkylamino or acylamino; and each R.sub.1 and R.sub.2 is alkyl; wherein the alkyl, alkoxy and aryl groups contain up to 10 carbon atoms and non-toxic, pharmaceutically-acceptable acid addition salts thereof.

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