Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1993-04-22
1994-10-25
Goldberg, Jerome D.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
A61K 3134
Patent
active
053589629
ABSTRACT:
An antihypertensive method comprising administering to a hypertensive patient a pharmaceutical agent containing lithospermic acid B represented by the formula: ##STR1## and/or the pharmaceutically acceptable salt thereof, for example, Mg.sup.2+, K.sup.+, NH.sub.4.sup.+ and Ca.sup.2+ salts thereof, as an effective ingredient.
REFERENCES:
Yokozawa, T. et al., "Magnesium Lithospermate B Suppressed the Proliferation of Mesangial Cells", Journal of Medical and Pharmaceutical Society for WAKAN-YAKU, vol. 9, 165-168, 1992.
Yokozawa, T. et al., "Effect of Magnesium Lithospermate B on the Renal and Urinary Kallikrein Activities in Rats and Adenine-Induced Renal Failure", Japanese Journal of Nephrology, vol. 35, No. 4, 1993.
Yokozawa, T. et al., "Inhibitory Effects of Crude Drug Components on the Proliferation of cultured Human Mesangial Cells", Japanese Journal of Nephrology, vol. 35, No. 4, 1993.
Yokozawa, T. et al., "Contribution of Prostaglandins to the Renal Responses to Magnesium Lithospermate B Isolated from Salviae Miltiorrhizae Radix", Chem. Pharm. Bull., 37(6) 1568-1571, vol. 37, No. 6, 1989.
Nishioka Itsuo
Oura Hikokichi
Takeuchi Tadao
Yokozawa Takako
Goldberg Jerome D.
Minophagen Pharmaceutical Company
LandOfFree
Antihypertensive method does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Antihypertensive method, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Antihypertensive method will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-135681