Antihypertensive cyanoguanidines

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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514222, 514237, 514253, 514256, 514316, 514321, 2602444, 544 586, 544 62, 544129, 544130, 544333, 544335, 544364, 546187, 546197, A61K 3155, C07D40506

Patent

active

045798451

ABSTRACT:
This invention relates to novel tri-substituted guanidines linked to a piperidine ring.
More specifically, it relates to cyanoguanidines of formula I ##STR1## wherein R.sub.1, R.sub.2, R.sub.3, R.sub.4 are substituents

REFERENCES:
patent: 3006913 (1961-10-01), Mull
patent: 3950333 (1976-04-01), Durant et al.
Chemical Abstracts, 93: 106809f (1980) [Archibald, J., et al., J. Med. Chem., 1980, 23(8), 857-61].

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